Influenza A NS1 Antikörper

Produktnummer ABIN7794992

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Influenza A NS1 in . Er zeigt eine Reaktivität gegenüber Avian Influenza Virus.

Kurzübersicht für Influenza A NS1 Antikörper (ABIN7794992)

Target: Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))

Reaktivität: Avian Influenza Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Influenza A NS1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-Influenza A NS1 Antikörper

Verwendungszweck: Anti-Avian Influenza Nonstructural Protein 1(H5N1 NS1)

Spezifität: Rabbit Anti-H5N1 NS1 recognizes H5N1 NS1. This polyclonal antibody was purified using affinity chromatography. Background Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however, it is in birds that all subtypes, including the so-called ?avian flu? or H5N1, can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2?-5? OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/mL

Buffer: This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02 % sodium azide as a preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Details zu Influenza A NS1

Target: Influenza A NS1 (NS1) (Influenza Non Structural 1 (NS1))

Andere Bezeichnung: Avian Influenza Nonstructural Protein 1

Substanzklasse: Influenza Protein